Antimycin A

抗霉素A/抗霉菌素A

说明：药物活性分子，琥珀酸氧化酶抑制剂。生物色素系统电子传递阻断剂。

细胞呼吸抑制剂。本产品仅用于科研。

Antimycin A is an antibiotic that induces apoptosis and inhibits the mitochondrial electron transport chain from cytochrome b to cytochrome C1. Additionally, studies report that antimycin A causes damage to mitochondrial DNA, lipids, and proteins in cells treated with the antibiotic. The compound has been shown to mimic cell-death-inducing Bcl-2 homology domain 3 and has been applied as a reactive oxygen species (ROS) generator to study biological systems. Research indicates that antimycin A inhibits the cell growth of HeLa cells through apoptosis and blocks nitric oxide-induced apoptosis via inhibition of cytochrome C leakage.